Cardiac Pharmacology: Difference between revisions

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|The concentration of drug needed to elicit a response halfway between zero and maximal responses.
|The concentration of drug needed to elicit a response halfway between zero and maximal responses.
|µg/ml (EC<sub>50</sub>)
|µg/ml (EC<sub>50</sub>)
|y=bottom+ (Top-Bottom)/(1+ [x/EC<sub>50</sub>] Hill Coefficient)
|align="center"|y = bottom + (Top-Bottom)/(1+ [x/EC50] Hill Coefficient)
|-
|-
!Volume of Distribution
!Volume of Distribution
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|How much of the administered dose is available for actual use by the body.
|How much of the administered dose is available for actual use by the body.
|no units as expressing a fraction (f)
|no units as expressing a fraction (f)
|100 ×  (AUC (po)×D (iv))/(AUC (iv)×D (po))
|align="center"|100 ×  (AUC (po)×D (iv))/(AUC (iv)×D (po))


AUC = Area under curve  po = oral administration  iv = intravenous administration
AUC = Area under curve  po = oral administration  iv = intravenous administration
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