Heart Failure: Difference between revisions

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120 bytes removed ,  3 November 2012
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*Captopril
*Captopril
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|
|Start:::6.25mg
|Start 6.25mg


1<sup>st</sup> week:::6.25mg three times daily.
1<sup>st</sup> week 6.25mg three times daily.


3-5 weeks:::12.5mg three times daily.
3-5 weeks 12.5mg three times daily.


>7 weeks:::25mg three times daily.
>7 weeks 25mg three times daily.
|-
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|valign="top"|
|valign="top"|
*Lisinopril
*Lisinopril
|
|
|Start:::2.5-5mg
|Start 2.5-5mg


1<sup>st</sup> week:::5-10mg once daily.
1<sup>st</sup> week 5-10mg once daily.


5-7 weeks:::25mg three times daily.
5-7 weeks 25mg three times daily.


>7 weeks:::50 mg three times daily.
>7 weeks 50 mg three times daily.
|-
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|valign="top"|
|valign="top"|
*Enalapril/quinalapril
*Enalapril/quinalapril
|
|
|Start:::2.5-5mg
|Start 2.5-5mg


1<sup>st</sup> week:::2.5-5mg twice daily.
1<sup>st</sup> week 2.5-5mg twice daily.


3-5 weeks:::5-10mg twice daily.
3-5 weeks 5-10mg twice daily.


>7 weeks:::10-20mg twice daily.
>7 weeks 10-20mg twice daily.
|-
|-
|bgcolor="#F0F0F0 " colspan="3"|'''Beta blockers'''
|bgcolor="#F0F0F0 " colspan="3"|'''Beta blockers'''
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*Metoprolol zoc (succinate)
*Metoprolol zoc (succinate)
|valign="top"|EF >30-45% and NYHA II-III
|valign="top"|EF >30-45% and NYHA II-III
|Start:::25mg
|Start 25mg


1<sup>st</sup> week:::50mg once daily.
1<sup>st</sup> week 50mg once daily.


3-5 weeks:::100mg once daily.
3-5 weeks 100mg once daily.


>7 weeks:::100-200mg once daily.
>7 weeks 100-200mg once daily.
|-
|-
|
|
|valign="top"|EF <30% and NYHA IV
|valign="top"|EF <30% and NYHA IV
|Start:::12.5mg
|Start 12.5mg


1<sup>st</sup> week:::25mg once daily.
1<sup>st</sup> week 25mg once daily.


3-5 weeks:::50mg once daily.
3-5 weeks 50mg once daily.


>7 weeks:::100-200mg once daily.
>7 weeks 100-200mg once daily.
|-
|-
|valign="top"|
|valign="top"|
*Bisoprolol
*Bisoprolol
|valign="top"|EF >30-45% and NYHA II-III
|valign="top"|EF >30-45% and NYHA II-III
|Start:::2.5mg
|Start 2.5mg


1<sup>st</sup> week:::3.75mg once daily.
1<sup>st</sup> week 3.75mg once daily.


3-5 weeks:::5mg once daily.
3-5 weeks 5mg once daily.


>7 weeks:::7.5-10mg once daily.
>7 weeks 7.5-10mg once daily.
|-
|-
|
|
|valign="top"|EF <30% and NYHA IV
|valign="top"|EF <30% and NYHA IV
|Start:::1.25mg
|Start 1.25mg


1<sup>st</sup> week:::2.5mg once daily.
1<sup>st</sup> week 2.5mg once daily.


3-5 weeks:::3.75mg once daily.
3-5 weeks 3.75mg once daily.


>7 weeks:::5-7.5-10mg once daily.
>7 weeks 5-7.5-10mg once daily.
|-
|-
|valign="top"|
|valign="top"|
*Carvedilol
*Carvedilol
|valign="top"|EF >30-45% and NYHA II-III
|valign="top"|EF >30-45% and NYHA II-III
|Start:::6.25mg
|Start 6.25mg


1<sup>st</sup> week:::6.25mg twice daily.
1<sup>st</sup> week 6.25mg twice daily.


3-5 weeks:::12.5mg twice daily.
3-5 weeks 12.5mg twice daily.


>7 weeks:::25mg twice daily.
>7 weeks 25mg twice daily.
|-
|-
|
|
|valign="top"|EF <30% and NYHA IV
|valign="top"|EF <30% and NYHA IV
|Start:::3.125mg
|Start 3.125mg


1<sup>st</sup> week:::3.125mg twice daily.
1<sup>st</sup> week 3.125mg twice daily.


3-5 weeks:::6.25mg twice daily.
3-5 weeks 6.25mg twice daily.


>7 weeks:::12.5-25mg twice daily.
>7 weeks 12.5-25mg twice daily.
|-
|-
|valign="top"|
|valign="top"|
*Nebivolol
*Nebivolol
|valign="top"|EF >30-45% and NYHA II-III
|valign="top"|EF >30-45% and NYHA II-III
|Start:::1.25mg
|Start 1.25mg


1<sup>st</sup> week:::2.5mg once daily.
1<sup>st</sup> week 2.5mg once daily.


3-5 weeks:::5mg once daily.
3-5 weeks 5mg once daily.


>7 weeks:::10mg once daily.
>7 weeks 10mg once daily.
|-
|-
|
|
|valign="top"|EF <30% and NYHA IV
|valign="top"|EF <30% and NYHA IV
|Start:::1.25mg
|Start 1.25mg


1<sup>st</sup> week:::2.5mg once daily.
1<sup>st</sup> week 2.5mg once daily.


3-5 weeks:::5mg once daily.
3-5 weeks 5mg once daily.


>7 weeks:::10mg once daily.
>7 weeks 10mg once daily.
|-
|-
|bgcolor="#F0F0F0 " colspan="3"|'''Aldosterone antagonist'''
|bgcolor="#F0F0F0 " colspan="3"|'''Aldosterone antagonist'''
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*Spironolactone/eplerenone
*Spironolactone/eplerenone
|
|
|Start:::25mg s.i.d.
|Start 25mg s.i.d.


1<sup>st</sup> week:::potassium <5.0: 25mg once daily.
1<sup>st</sup> week potassium <5.0: 25mg once daily.


potassium 5.0-5.5: 12.5mg once daily.
potassium 5.0-5.5: 12.5mg once daily.
Line 845: Line 845:
potassium >5.5: stop
potassium >5.5: stop


3rd week:::potassium <5.0: 25mg once daily.
3rd week potassium <5.0: 25mg once daily.


potassium 5.0-5.5: 12.5mg once daily.
potassium 5.0-5.5: 12.5mg once daily.
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*Digoxin
*Digoxin
|
|
|Start:::0.5mg, 0.25mg and 0,25 mg, each with 6 hours in between
|Start 0.5mg, 0.25mg and 0,25 mg, each with 6 hours in between


Continue with 0.25mg once daily.
Continue with 0.25mg once daily.
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*Candesartan
*Candesartan
|
|
|Start:::4mg
|Start 4mg


3-5 weeks:::8mg once daily.
3-5 weeks 8mg once daily.


>7 weeks:::16mg once daily.
>7 weeks 16mg once daily.
|-
|-
|valign="top"|
|valign="top"|
*Valsartan
*Valsartan
|
|
|Start:::80mg
|Start 80mg


3-5 weeks:::160mg once daily.
3-5 weeks 160mg once daily.


>7 weeks:::320mg once daily.
>7 weeks 320mg once daily.
|-
|-
|colspan="3" bgcolor="#F0F0F0 "|'''Hydralazine and isosorbide dinitrate (H-ISDN)'''
|colspan="3" bgcolor="#F0F0F0 "|'''Hydralazine and isosorbide dinitrate (H-ISDN)'''
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*Hydralazine
*Hydralazine
|
|
|Start:::25mg three times daily.
|Start 25mg three times daily.


3-5 weeks:::50mg three times daily.
3-5 weeks 50mg three times daily.


>7 weeks:::75-100mg three times daily.
>7 weeks 75-100mg three times daily.
|-
|-
|valign="top"|
|valign="top"|
*ISDN
*ISDN
|
|
|Start:::20mg twice daily
|Start 20mg twice daily


3-5 weeks:::40mg twice daily
3-5 weeks 40mg twice daily


>7 weeks:::80mg twice daily
>7 weeks 80mg twice daily
|}
|}


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