Heart Failure: Difference between revisions

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*Furosemide
*Furosemide
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|valign="bottom"|
Renal failure
|40 mg  
|40 mg  
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80 mg – max 1000 mg
|Renal failure
|80 mg – max 1000 mg
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*Bumetanide
*Bumetanide
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|valign="bottom"|
Renal failure
|1 mg
|1 mg
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2 mg – max 25 mg  
|Renal failure
|2 mg – max 25 mg  
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|'''ACE inhibitors'''
|'''ACE inhibitors'''
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|valign="top"|
*Captopril
*Captopril
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>7 weeks:::25mg three times daily.
>7 weeks:::25mg three times daily.
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|valign="top"|
*Lisinopril
*Lisinopril
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|Start:::2.5-5mg
|Start:::2.5-5mg
1<sup>st</sup> week:::5-10mg once daily.
5-7 weeks:::25mg three times daily.
>7 weeks:::50 mg three times daily.
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|valign="top"|
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|1<sup>st</sup> week:::5-10mg once daily.
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|5-7 weeks:::25mg three times daily.
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|>7 weeks:::50 mg three times daily.
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*Enalapril/quinalapril
*Enalapril/quinalapril
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|Start:::2.5-5mg
|Start:::2.5-5mg
1<sup>st</sup> week:::2.5-5mg twice daily.
3-5 weeks:::5-10mg twice daily.
>7 weeks:::10-20mg twice daily.
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|colspan="3"|'''Beta blockers'''
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|1<sup>st</sup> week:::2.5-5mg twice daily.
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|3-5 weeks:::5-10mg twice daily.
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|valign="top"|
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|>7 weeks:::10-20mg twice daily.
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|'''Beta blockers'''
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*Metoprolol zoc (succinate)
*Metoprolol zoc (succinate)
|EF >30-45% and NYHA II-III
|valign="top"|EF >30-45% and NYHA II-III
|Start:::25mg
|Start:::25mg
1<sup>st</sup> week:::50mg once daily.
3-5 weeks:::100mg once daily.
>7 weeks:::100-200mg once daily.
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|valign="top"|EF <30% and NYHA IV
|1<sup>st</sup> week:::50mg once daily.
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|3-5 weeks:::100mg once daily.
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|>7 weeks:::100-200mg once daily.
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|EF <30% and NYHA IV
|Start:::12.5mg
|Start:::12.5mg
1<sup>st</sup> week:::25mg once daily.
3-5 weeks:::50mg once daily.
>7 weeks:::100-200mg once daily.
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|valign="top"|
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|1<sup>st</sup> week:::25mg once daily.
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|3-5 weeks:::50mg once daily.
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|>7 weeks:::100-200mg once daily.
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*'''Bisoprolol'''
*'''Bisoprolol'''
|EF >30-45% and NYHA II-III
|valign="top"|EF >30-45% and NYHA II-III
|Start:::2.5mg
|Start:::2.5mg
1<sup>st</sup> week:::3.75mg once daily.
3-5 weeks:::5mg once daily.
>7 weeks:::7.5-10mg once daily.
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|valign="top"|EF <30% and NYHA IV
|1<sup>st</sup> week:::3.75mg once daily.
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|3-5 weeks:::5mg once daily.
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|>7 weeks:::7.5-10mg once daily.
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|EF <30% and NYHA IV
|Start:::1.25mg
|Start:::1.25mg
1<sup>st</sup> week:::2.5mg once daily.
3-5 weeks:::3.75mg once daily.
>7 weeks:::5-7.5-10mg once daily.
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|valign="top"|
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|1<sup>st</sup> week:::2.5mg once daily.
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|3-5 weeks:::3.75mg once daily.
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|>7 weeks:::5-7.5-10mg once daily.
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*'''Carvedilol'''
*'''Carvedilol'''
|EF >30-45% and NYHA II-III
|valign="top"|EF >30-45% and NYHA II-III
|Start:::6.25mg
|Start:::6.25mg
1<sup>st</sup> week:::6.25mg twice daily.
3-5 weeks:::12.5mg twice daily.
>7 weeks:::25mg twice daily.
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|valign="top"|EF <30% and NYHA IV
|1<sup>st</sup> week:::6.25mg twice daily.
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|3-5 weeks:::12.5mg twice daily.
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|>7 weeks:::25mg twice daily.
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|EF <30% and NYHA IV
|Start:::3.125mg
|Start:::3.125mg
1<sup>st</sup> week:::3.125mg twice daily.
3-5 weeks:::6.25mg twice daily.
>7 weeks:::12.5-25mg twice daily.
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|valign="top"|
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|1<sup>st</sup> week:::3.125mg twice daily.
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|3-5 weeks:::6.25mg twice daily.
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|>7 weeks:::12.5-25mg twice daily.
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*'''Nebivolol'''
*'''Nebivolol'''
|EF >30-45% and NYHA II-III
|valign="top"|EF >30-45% and NYHA II-III
|Start:::1.25mg
|Start:::1.25mg
1<sup>st</sup> week:::2.5mg once daily.
3-5 weeks:::5mg once daily.
>7 weeks:::10mg once daily.
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|valign="top"|EF <30% and NYHA IV
|1<sup>st</sup> week:::2.5mg once daily.
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|3-5 weeks:::5mg once daily.
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|>7 weeks:::10mg once daily.
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|EF <30% and NYHA IV
|Start:::1.25mg
|Start:::1.25mg
1<sup>st</sup> week:::2.5mg once daily.
3-5 weeks:::5mg once daily.
>7 weeks:::10mg once daily.
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|colspan="3"|'''Aldosterone antagonist'''
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|1<sup>st</sup> week:::2.5mg once daily.
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|3-5 weeks:::5mg once daily.
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|>7 weeks:::10mg once daily.
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|'''Aldosterone antagonist'''
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|Start:::25mg s.i.d.
|Start:::25mg s.i.d.
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1<sup>st</sup> week:::potassium <5.0: 25mg once daily.
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|1<sup>st</sup> week:::potassium <5.0: 25mg once daily.
potassium 5.0-5.5: 12.5mg once daily.
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potassium >5.5: stop
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|potassium 5.0-5.5: 12.5mg once daily.
3rd week:::potassium <5.0: 25mg once daily.
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potassium 5.0-5.5: 12.5mg once daily.
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|potassium >5.5: stop
potassium >5.5: stop
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|3rd week:::potassium <5.0: 25mg once daily.
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|potassium 5.0-5.5: 12.5mg once daily.
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|potassium >5.5: stop
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|'''Digoxin'''
|'''Digoxin'''
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|Start:::0.5mg, 0.25mg and 0,25 mg, each with 6 hours in between
|Start:::0.5mg, 0.25mg and 0,25 mg, each with 6 hours in between
Continue with 0.25mg once daily.
Half dose with age above 70 or creatinin above 110 or with amiodarone use
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|colspan="3"|'''AT II blockers'''
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|Continue with 0.25mg once daily.
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|Half dose with age above 70 or creatinin above 110 or with amiodarone use
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|'''AT II blockers'''
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|Start:::4mg
|Start:::4mg
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3-5 weeks:::8mg once daily.
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|3-5 weeks:::8mg once daily.
>7 weeks:::16mg once daily.
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|>7 weeks:::16mg once daily.
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|Start:::80mg
|Start:::80mg
3-5 weeks:::160mg once daily.
>7 weeks:::320mg once daily.
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|colspan="3"|'''Hydralazine and isosorbide dinitrate (H-ISDN)'''
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|3-5 weeks:::160mg once daily.
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|>7 weeks:::320mg once daily.
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|'''Hydralazine and isosorbide dinitrate (H-ISDN)'''
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|Start:::25mg three times daily.
|Start:::25mg three times daily.
|-
 
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3-5 weeks:::50mg three times daily.
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|3-5 weeks:::50mg three times daily.
>7 weeks:::75-100mg three times daily.
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|>7 weeks:::75-100mg three times daily.
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|Start:::20mg twice daily
|Start:::20mg twice daily
|-
 
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3-5 weeks:::40mg twice daily
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|3-5 weeks:::40mg twice daily
>7 weeks:::80mg twice daily
|-
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|>7 weeks:::80mg twice daily
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