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LQTS: Difference between revisions
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*The diagnosis is by measurement of the heart rate corrected QT interval on the ECG, which can be calculated with the [[QTc calculator]]. | *The diagnosis is by measurement of the heart rate corrected QT interval on the ECG, which can be calculated with the [[QTc calculator]]. | ||
*Sometimes the QT interval can be difficult to assess. Read the [[guidelines for measurement of difficult QT interval]]. | *Sometimes the QT interval can be difficult to assess. Read the [[guidelines for measurement of difficult QT interval]]. | ||
*A QTc of > 500ms in patients with Long QT Syndrome is associated with an increased risk of torsade de pointes and sudden death. <cite> | *A QTc of > 500ms in patients with Long QT Syndrome is associated with an increased risk of torsade de pointes and sudden death. <cite>priori</cite> | ||
*In patients suspected of LQTS (e.g. family members of known LQTS patients) a QTc > 430ms makes it likely that a LQTS gene defect is present.<cite>Hofman</cite> | *In patients suspected of LQTS (e.g. family members of known LQTS patients) a QTc > 430ms makes it likely that a LQTS gene defect is present.<cite>Hofman</cite> | ||
*Because the QTc can change with age, it is best to take the ECG with the longest QTc interval for risk stratification. <cite>Goldenberg</cite> | *Because the QTc can change with age, it is best to take the ECG with the longest QTc interval for risk stratification. <cite>Goldenberg</cite> | ||