Myocardial Infarction: Difference between revisions

Jump to navigation Jump to search
No edit summary
(7 intermediate revisions by 2 users not shown)
Line 64: Line 64:


===Non-ST-segment elevation Acute Coronary Syndrome===
===Non-ST-segment elevation Acute Coronary Syndrome===
 
[[Image:Swe.jpg|thumb|right|400px|link=http://www.outcomes-umassmed.org/grace/acs_risk/acs_risk_content.html|The [http://www.outcomes-umassmed.org/grace/acs_risk/acs_risk_content.html GRACE risk score model]]]
Comparable to STEMI, revascularization in NSTE-ACS relieves symptoms, shortens hospital
Comparable to STEMI, revascularization in NSTE-ACS relieves symptoms, shortens hospital
stay, and improves prognosis. However, NSTE-ACS patients represent a heterogenous population, and indication and timing of revascularization depend on many factors, including the baseline risk of the patient. According to current guidelines, depending on early risk stratification a choice has to be made between a routine invasive or a selective invasive (or “conservative strategy”) <Cite>REFNAME27</Cite>
stay, and improves prognosis. However, NSTE-ACS patients represent a heterogenous population, and indication and timing of revascularization depend on many factors, including the baseline risk of the patient. According to current guidelines, depending on early risk stratification a choice has to be made between a routine invasive or a selective invasive (or “conservative strategy”) <Cite>REFNAME27</Cite>
Line 70: Line 70:
Early risk stratification is helpful to identify patients at high risk who might benefit the most from a more aggressive therapeutic approach in order to prevent further ischemic events. <Cite>REFNAME28</Cite>
Early risk stratification is helpful to identify patients at high risk who might benefit the most from a more aggressive therapeutic approach in order to prevent further ischemic events. <Cite>REFNAME28</Cite>


{| class="wikitable" cellpadding="0" cellspacing="0" width="600px"
{| class="wikitable" cellpadding="0" cellspacing="0" border="0" width="500px"
|-
|colspan="3" bgcolor="33CCFF"|
|-
|colspan="3" align="center"|'''Non STE-ACS: In-hospital Mortality'''
|-
|-
|colspan="3" bgcolor="33CCFF"|
|colspan="5" align="center"|'''GRACE risk score'''
|-
|-
!Risk Category (tertiles)
!Risk Category
!GRACE Risk Score
!low
!Probability of Death In-hospital (%)
!Intermediate
!High
|-
|-
|Low
|NSTEMI Probability of Death In-hospital (%)
|1-108
|<1
|<1
|-
|1-3
|Intermediate
|109-140
|1-3
|-
|High
|141-372
|>3
|>3
|}
{| class="wikitable" cellpadding="0" cellspacing="0" width="600px"
|-
|colspan="3" bgcolor="33CCFF"|
|-
|colspan="3" align="center"|'''Non STE-ACS: 6 Month Post-discharge Mortality'''
|-
|colspan="3" bgcolor="33CCFF"|
|-
!Risk Category (tertiles)
!GRACE Risk Score
!Probability of Death Post-discharge to 6 Months (%)
|-
|-
|Low
|NSTEMI 6 Month Post-discharge Mortality
|1-88
|<3
|<3
|-
|Intermediate
|89-118
|3-8
|3-8
|-
|High
|119-263
|>8
|>8
|}
{| class="wikitable" cellpadding="0" cellspacing="0" width="600px"
|-
|-
|colspan="3" bgcolor="33CCFF"|
|STEMI In-hospital Mortality (%)
|-
|colspan="3" align="center"|'''STE-ACS: In-hospital Mortality'''
|-
|colspan="3" bgcolor="33CCFF"|
|-
!Risk Category (tertiles)
!GRACE Risk Score
!Probability of Death In-hospital (%)
|-
|Low
|49-125
|<2
|<2
|-
|Intermediate
|126-154
|2-5
|2-5
|-
|High
|155-319
|>5
|>5
|}
{| class="wikitable" cellpadding="0" cellspacing="0" width="600px"
|-
|-
|colspan="3" bgcolor="33CCFF"|
|STEMI 6 Month Post-discharge Mortality
|-
|colspan="3" align="center"|'''STE-ACS: 6 Month Post-discharge Mortality'''
|-
|colspan="3" bgcolor="33CCFF"|
|-
!Risk Category (tertiles)
!GRACE Risk Score
!Probability of Death Post-discharge to 6 Months (%)
|-
|Low
|27-99
|<4.4
|<4.4
|-
|Intermediate
|100-127
|4.5-11
|4.5-11
|-
|High
|128-263
|>11
|>11
|}
|}
[[Image:Swe.jpg|thumb|right|400px|The GRACE risk score model]]


Early risk stratification can be performed using one of the validated risk scores, such as the GRACE risk score. GRACE calculates the probability of death while in hospital. The following characteristics are taken into account:
Early risk stratification can be performed using one of the validated risk scores, such as the GRACE risk score. GRACE calculates the probability of death while in hospital. The following characteristics are taken into account:
Line 192: Line 120:


====Cardiac rehabilitation====
====Cardiac rehabilitation====
Cardiac rehabilitation reduces mortality, helps the patient to regain confidence and to resocialise, and helps to reduce risk factors for atherosclerosis. Post-ACS patient should be referred for cardiac rehabilitation.  
Cardiac rehabilitation reduces mortality, helps the patient to regain confidence and to resocialise, and helps to reduce risk factors for atherosclerosis. Post-ACS patient should be referred for cardiac rehabilitation.
 
== References ==
== References ==
<biblio>
<biblio>

Navigation menu