Myocardial Infarction: Difference between revisions

Jump to navigation Jump to search
No edit summary
(8 intermediate revisions by 2 users not shown)
Line 64: Line 64:


===Non-ST-segment elevation Acute Coronary Syndrome===
===Non-ST-segment elevation Acute Coronary Syndrome===
 
[[Image:Swe.jpg|thumb|right|400px|link=http://www.outcomes-umassmed.org/grace/acs_risk/acs_risk_content.html|The [http://www.outcomes-umassmed.org/grace/acs_risk/acs_risk_content.html GRACE risk score model]]]
Comparable to STEMI, revascularization in NSTE-ACS relieves symptoms, shortens hospital
Comparable to STEMI, revascularization in NSTE-ACS relieves symptoms, shortens hospital
stay, and improves prognosis. However, NSTE-ACS patients represent a heterogenous population, and indication and timing of revascularization depend on many factors, including the baseline risk of the patient. According to current guidelines, depending on early risk stratification a choice has to be made between a routine invasive or a selective invasive (or “conservative strategy”) <Cite>REFNAME27</Cite>
stay, and improves prognosis. However, NSTE-ACS patients represent a heterogenous population, and indication and timing of revascularization depend on many factors, including the baseline risk of the patient. According to current guidelines, depending on early risk stratification a choice has to be made between a routine invasive or a selective invasive (or “conservative strategy”) <Cite>REFNAME27</Cite>
Line 70: Line 70:
Early risk stratification is helpful to identify patients at high risk who might benefit the most from a more aggressive therapeutic approach in order to prevent further ischemic events. <Cite>REFNAME28</Cite>
Early risk stratification is helpful to identify patients at high risk who might benefit the most from a more aggressive therapeutic approach in order to prevent further ischemic events. <Cite>REFNAME28</Cite>


{| class="wikitable" cellpadding="0" cellspacing="0" width="600px"
{| class="wikitable" cellpadding="0" cellspacing="0" border="0" width="500px"
|-
|colspan="3" bgcolor="33CCFF"|
|-
|colspan="3" align="center"|'''Non STE-ACS: In-hospital Mortality'''
|-
|-
|colspan="3" bgcolor="33CCFF"|
|colspan="5" align="center"|'''GRACE risk score'''
|-
|-
!Risk Category (tertiles)
!Risk Category
!GRACE Risk Score
!low
!Probability of Death In-hospital (%)
!Intermediate
!High
|-
|-
|Low
|NSTEMI Probability of Death In-hospital (%)
|1-108
|<1
|<1
|-
|1-3
|Intermediate
|109-140
|1-3
|-
|High
|141-372
|>3
|>3
|}
{| class="wikitable" cellpadding="0" cellspacing="0" width="600px"
|-
|-
|colspan="3" bgcolor="33CCFF"|
|NSTEMI 6 Month Post-discharge Mortality
|-
|colspan="3" align="center"|'''Non STE-ACS: 6 Month Post-discharge Mortality'''
|-
|colspan="3" bgcolor="33CCFF"|
|-
!Risk Category (tertiles)
!GRACE Risk Score
!Probability of Death Post-discharge to 6 Months (%)
|-
|Low
|1-88
|<3
|<3
|-
|Intermediate
|89-118
|3-8
|3-8
|-
|High
|119-263
|>8
|>8
|}
{| class="wikitable" cellpadding="0" cellspacing="0" width="600px"
|-
|colspan="3" bgcolor="33CCFF"|
|-
|colspan="3" align="center"|'''STE-ACS: In-hospital Mortality'''
|-
|colspan="3" bgcolor="33CCFF"|
|-
!Risk Category (tertiles)
!GRACE Risk Score
!Probability of Death In-hospital (%)
|-
|-
|Low
|STEMI In-hospital Mortality (%)
|49-125
|<2
|<2
|-
|Intermediate
|126-154
|2-5
|2-5
|-
|High
|155-319
|>5
|>5
|}
{| class="wikitable" cellpadding="0" cellspacing="0" width="600px"
|-
|-
|colspan="3" bgcolor="33CCFF"|
|STEMI 6 Month Post-discharge Mortality
|-
|colspan="3" align="center"|'''STE-ACS: 6 Month Post-discharge Mortality'''
|-
|colspan="3" bgcolor="33CCFF"|
|-
!Risk Category (tertiles)
!GRACE Risk Score
!Probability of Death Post-discharge to 6 Months (%)
|-
|Low
|27-99
|<4.4
|<4.4
|-
|Intermediate
|100-127
|4.5-11
|4.5-11
|-
|High
|128-263
|>11
|>11
|}
|}
Line 190: Line 120:


====Cardiac rehabilitation====
====Cardiac rehabilitation====
Cardiac rehabilitation reduces mortality, helps the patient to regain confidence and to resocialise, and helps to reduce risk factors for atherosclerosis. Post-ACS patient should be referred for cardiac rehabilitation.  
Cardiac rehabilitation reduces mortality, helps the patient to regain confidence and to resocialise, and helps to reduce risk factors for atherosclerosis. Post-ACS patient should be referred for cardiac rehabilitation.
 
== References ==
== References ==
<biblio>
<biblio>

Navigation menu