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Valvular Heart Disease: Difference between revisions
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In infancy, bicuspid aortic valve disease is often asymptomatic. By adolescence an estimate 1 of 50 children born with these abnormalities will have clinically significant obstruction or regurgitation. <cite>Bonow2</cite> | In infancy, bicuspid aortic valve disease is often asymptomatic. By adolescence an estimate 1 of 50 children born with these abnormalities will have clinically significant obstruction or regurgitation. <cite>Bonow2</cite> | ||
Complications of bicuspid aortic valve disease are common in adulthood <cite>Tzemos</cite>. The abnormal shear stress leads to valve calcification and further aortic root dilation has been reported. <cite>Bonow3/cite> The most common complication is aortic stenosis, caused by premature fibrosis, stiffening, and calcium deposition. The majority of patients under 65 years of age with significant aortic valve stenosis have bicuspid aortic valve disease. A more rare complication of bicuspid aortic valve disease is aortic regurgitation. 15% of all cases of aortic regurgitation in the Euro Heart survey had bicuspid aortic valve disease. On auscultation, an ejection sound can be audible, best heard at the apex. There may be associated murmurs of aortic stenosis, incompetence, or coarctation of the aorta when these lesions are present. | Complications of bicuspid aortic valve disease are common in adulthood <cite>Tzemos</cite>. The abnormal shear stress leads to valve calcification and further aortic root dilation has been reported. <cite>Bonow3</cite> The most common complication is aortic stenosis, caused by premature fibrosis, stiffening, and calcium deposition. The majority of patients under 65 years of age with significant aortic valve stenosis have bicuspid aortic valve disease. A more rare complication of bicuspid aortic valve disease is aortic regurgitation. 15% of all cases of aortic regurgitation in the Euro Heart survey had bicuspid aortic valve disease. On auscultation, an ejection sound can be audible, best heard at the apex. There may be associated murmurs of aortic stenosis, incompetence, or coarctation of the aorta when these lesions are present. | ||
=== Diagnostic options === | === Diagnostic options === | ||