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Grown-up Congenital Heart Disease (GUCH): Difference between revisions
Grown-up Congenital Heart Disease (GUCH) (view source)
Revision as of 15:15, 25 January 2012
, 25 January 2012→Introduction
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=== Case report === | === Case report === | ||
=== Introduction === | === Introduction === | ||
[[File:18. MFS.jpg|thumb|left|Figure 18. Echocardiographic image of aortic root dilatation in Marfan syndrome.]] | |||
[[File:19. MFS2.jpg|thumb|right|Figure 19. Magnetic resonance imaging of the aorta, showing aortic root dilatation in Marfan syndrome.]] | |||
Marfan syndrome (MFS) is an autosomal dominant condition with a reported incidence of 1 in 3000 to 5000 individuals and is one of the most common inherited disorders of connective tissue. While most MFS patients have an affected parent, around 15 – 30 percent have a de novo mutation. MFS is associated with a broad range of clinical symptoms and associated disorders, ranging from classic ocular, cardiovascular, and musculoskeletal abnormalities to manifestations including involvement of the lung, skin, and central nervous system. | Marfan syndrome (MFS) is an autosomal dominant condition with a reported incidence of 1 in 3000 to 5000 individuals and is one of the most common inherited disorders of connective tissue. While most MFS patients have an affected parent, around 15 – 30 percent have a de novo mutation. MFS is associated with a broad range of clinical symptoms and associated disorders, ranging from classic ocular, cardiovascular, and musculoskeletal abnormalities to manifestations including involvement of the lung, skin, and central nervous system. | ||