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Brugada Syndrome: Difference between revisions
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|colspan="6" bgcolor="#FFFFCC"|'''OMIM:''' ''Online Mendelian Inheritance in Man'' compendium of human genes and genetic phenotypes; '''BrS1–BrS7:''' Brugada syndrome types 1–7; '''NC:''' no consensus; '''I<sub>Ca,L</sub>:''' L-type calcium current; '''I<sub>f</sub>:''' hyperpolarization-activated current; '''I<sub>K,ATP</sub>:''' ATP-sensitive potassium current; '''I<sub>Na</sub>:''' fast sodium current; '''I<sub>to</sub>:''' transient outward potassium current. | |colspan="6" bgcolor="#FFFFCC"|'''OMIM:''' ''Online Mendelian Inheritance in Man'' compendium of human genes and genetic phenotypes; '''BrS1–BrS7:''' Brugada syndrome types 1–7; '''NC:''' no consensus; '''I<sub>Ca,L</sub>:''' L-type calcium current; '''I<sub>f</sub>:''' hyperpolarization-activated current; '''I<sub>K,ATP</sub>:''' ATP-sensitive potassium current; '''I<sub>Na</sub>:''' fast sodium current; '''I<sub>to</sub>:''' transient outward potassium current. | ||
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==Physical examination== | |||
Patients can present with symptoms of arrhythmias: | |||
*Out-of-hospital-cardiac-arrest | |||
*Syncope, pre-syncope (weakness, lightheadedness, dizziness) | |||
*Chest pain | |||
*Shortness of breath | |||
*Paleness | |||
*Sweating | |||
Other clinical presentations of Brugada syndrome may include sudden infant death syndrome (SIDS) and sudden unexpected nocturnal death syndrome (SUDS), which is seen in southeast Asia in which young persons die from cardiac arrest with no identifiable cause (also known as ''bangungut'' in the Philippines, ''lai tai'' in Thailand, ''pokkuri'' in Japan and ''dab tsog'' in Laos. | |||
However, most patients with Brugada syndrome are asymptomatic and are under medical attention because of family screening for sudden cardiac death/Brugada syndrome or because a Brugada ECG was found coincidentally. | |||
==Diagnosis and treatment== | ==Diagnosis and treatment== | ||